The Okefinokee Route Nickname of the Waycross and Southern Railroad. The W&S ran from Waycross to Hopkins at the edge of the Okefenokee Swamp from about 1912 to 1928. Note: Okefinokee is an alternate spelling of Okefenokee.   RailGa.com. Georgia's Railroad History & Heritage. © Steve Storey Railroad History | The Depot List | Locomotives On Display | Odds & Ends | Sources & References | Home